Time Magazine: Inflammation Part 2 of 8

"....At least that's the theory. For now, most of the evidence is circumstantial. (A few researchers think chronic inflammation can in some cases be good for you.) But that hasn't stopped doctors from testing the anti-inflammatory drugs that are already on pharmacy shelves to see if they have any broader benefits. What they've found is encouraging:

— In 2000 researchers concluded that patients who take Celebrex, a prescription drug from Pfizer that was originally designed to treat inflammation in arthritis, are less likely to develop intestinal polyps — abnormal growths that can become cancerous. Now there are dozens of clinical trials of Celebrex, testing, among other things, whether the medication can also prevent breast cancer, delay memory loss or slow the progression of the devastating neurodegenerative disorder known as Lou Gehrig's disease.

— As cardiologists gain more experience prescribing cholesterol-lowering statins, they are discovering that the drugs are more effective at preventing heart attacks than anyone expected. It turns out that statins don't just lower cholesterol levels; they also reduce inflammation. Now statins are being tested for their anti-inflammatory effects on Alzheimer's disease and sickle-cell anemia.

DeCode Genetics, an Icelandic biotech firm, announced last week that it is launching a pilot study to test whether an anti-inflammatory drug that was under development for use in treating asthma might work to prevent heart attacks.

— Of course the granddaddy of all anti-inflammatories is aspirin, and millions of Americans already take it to prevent heart attacks. But evidence is growing that it may also fight colon cancer and even Alzheimer's by reducing inflammation in the digestive tract and the brain.

This new view of inflammation is changing the way some scientists do medical research. "Virtually our entire R.-and-D. effort is [now] focused on inflammation and cancer," says Dr. Robert Tepper, president of research and development at Millennium Pharmaceuticals in Cambridge, Mass. In medical schools across the U.S., cardiologists, rheumatologists, oncologists, allergists and neurologists are all suddenly talking to one another — and they're discovering that they're looking at the same thing. The speed with which researchers are jumping on the inflammation bandwagon is breathtaking. Just a few years ago, "nobody was interested in this stuff," says Dr. Paul Ridker, a cardiologist at Brigham and Women's Hospital who has done some of the groundbreaking work in the area. "Now the whole field of inflammation research is about to explode."

To understand better what all the excitement is about, it helps to know a little about the basic immunological response, a cascade of events triggered whenever the body is subjected to trauma or injury. As soon as that splinter slices into your finger, for example, specialized sentinel cells prestationed throughout the body alert the immune system to the presence of any bacteria that might have come along for the ride. Some of those cells, called mast cells, release a chemical called histamine that makes nearby capillaries leaky. This allows small amounts of plasma to pour out, slowing down invading bacteria, and prepares the way for other faraway immune defenders to easily enter the fray. Meanwhile, another group of sentinels, called macrophages, begin an immediate counterattack and release more chemicals, called cytokines, which signal for reinforcements. Soon, wave after wave of immune cells flood the site, destroying pathogens and damaged tissue alike — there's no carrying the wounded off the battlefield in this war. (No wonder the ancient Romans likened inflammation to being on fire.)

Doctors call this generalized response to practically any kind of attack innate immunity. Even the bodies of animals as primitive as starfish defend themselves this way. But higher organisms have also developed a more precision-guided defense system that helps direct and intensify the innate response and creates specialized antibodies, custom-made to target specific kinds of bacteria or viruses. This so-called learned immunity is what enables drug companies to develop vaccines against diseases like smallpox and the flu. Working in tandem, the innate and learned immunological defenses fight pitched battles until all the invading germs are annihilated. In a final flurry of activity, a last wave of cytokines is released, the inflammatory process recedes, and healing begins.

Problems begin when, for one reason or another, the inflammatory process persists and becomes chronic; the final effects are varied and depend a lot on where in the body the runaway reaction takes hold. Among the first to recognize the broader implications were heart doctors who noticed that inflammation seems to play a key role in cardiovascular disease."

Time Magazine: Inflammation Part 1 of 8

     A friend of mine who is a strong advocate for Trivita as well as the world's health and wellness sent me this article from Time magazine! It is pretty long, so I broke it up for an easy read because it is such pertinent information in the world today! With the leading killers in America having such relation to inflammation, you can't afford not to know!

"What does a stubbed toe or a splinter in a finger have to do with your risk of developing Alzheimer's disease, suffering a heart attack or succumbing to colon cancer? More than you might think. As scientists delve deeper into the fundamental causes of those and other illnesses, they are starting to see links to an age-old immunological defense mechanism called inflammation — the same biological process that turns the tissue around a splinter red and causes swelling in an injured toe. If they are right — and the evidence is starting to look pretty good — it could radically change doctors' concept of what makes us sick. It could also prove a bonanza to pharmaceutical companies looking for new ways to keep us well.

Most of the time, inflammation is a lifesaver that enables our bodies to fend off various disease-causing bacteria, viruses and parasites. (Yes, even in the industrialized world, we are constantly bombarded by pathogens.) The instant any of these potentially deadly microbes slips into the body, inflammation marshals a defensive attack that lays waste to both invader and any tissue it may have infected. Then just as quickly, the process subsides and healing begins.

Every once in a while, however, the whole feverish production doesn't shut down on cue. Sometimes the problem is a genetic predisposition; other times something like smoking or high blood pressure keeps the process going. In any event, inflammation becomes chronic rather than transitory. When that occurs, the body turns on itself — like an ornery child who can't resist picking a scab — with aftereffects that seem to underlie a wide variety of diseases.

Suddenly, inflammation has become one of the hottest areas of medical research. Hardly a week goes by without the publication of yet another study uncovering a new way that chronic inflammation does harm to the body. It destabilizes cholesterol deposits in the coronary arteries, leading to heart attacks and potentially even strokes. It chews up nerve cells in the brains of Alzheimer's victims. It may even foster the proliferation of abnormal cells and facilitate their transformation into cancer. In other words, chronic inflammation may be the engine that drives many of the most feared illnesses of middle and old age.

This concept is so intriguing because it suggests a new and possibly much simpler way of warding off disease. Instead of different treatments for, say, heart disease, Alzheimer's and colon cancer, there might be a single, inflammation-reducing remedy that would prevent all three.

Chronic inflammation also fascinates scientists because it indicates that our bodies may have, from an evolutionary perspective, become victims of their own success. "We evolved as a species because of our ability to fight off microbial invaders," says Dr. Peter Libby, chief of cardiovascular medicine at Brigham and Women's Hospital in Boston. "The strategies our bodies used for survival were important in a time when we didn't have processing plants to purify our water, when we didn't have sewers to protect us."

But now that we are living longer, those same inflammatory strategies are more likely to slip beyond our control. Making matters worse, it appears that many of the attributes of a Western lifestyle — such as a diet high in sugars and saturated fats, accompanied by little or no exercise — also make it easier for the body to become inflamed."

... to be continued.

Nopalea Challenge: Day 10

Hey, my family and friends! This superfruit has really made my life easier! Who all can stand life being a little easier? Man, it is SOOO exciting! So, this challenge lasted 10 days for me; it is up to you since you take 3-6 ounces a day. I took basically 3oz. for 10 days!

Sonoran Bloom Nopalea has made such a difference when I workout! My knees no longer hurt; I feel like I can go all day! It is soo refreshing to be able to run at the gym and not feel like I need to prop my knees up afterwards... finally, my mind won't beat up my body for not being able to keep up!

Also, Sonoran Bloom has improved my skin! I feel so great! Clear skin is always exciting! I used to get headaches on a weekly basis... after a month on Nopalea... no headaches for me! I will stay on Sonoran Bloom for life!

If you have any kind of inflammation in your body, Sonoran Bloom can really make a difference! If you are interested in experiencing wellness, you can visit www.sonoranbloom.com/13380527 or e-mail me @ kelkins@elkinsgroup.com! Look forward to hearing your success story!

Nopalea Challenge: Day 5

Never in 5 days have I ever wanted to make a commitment to something or even someone! Good things are suppose to take time?... Or so I thought!

I have come to find that Nopalea can be extremely, tremendously helpful to women who suffer from the severest of menstrual symptoms! The discomfort that comes with nature's gift can sometime be enabling. Never would I have thought it would be helpful for this, but it addresses the inflammation in our body! I never put menstrual cycles in the category of inflammation, but it is!

There is a normal inflammatory response during the cycle: estrogen and progesterone build up during the cycle, arachidonic acid. This is stored with the uterine muscles. This acid is a precursor to a lot of inflammation. So an inflammatory diet including red meats, chicken, egg yolks, and some oils can increase the cramping! Our recommended daily intake of carbohydrates should account for 60% of our daily intake. Limiting the amount of these proteins could help!

And all the women screamed Hallelujah! Nopalea just made our lives easier and allowing us to be productive all the days of the month not just 28 or 29!

Nopalea: World's Only Inflammatory Supplement

To My Readers,

I am all about bringing you the best knowledge I can find that I see can benefit you or has personally helped me be healthier and stronger! I just have one question for YOU! If  there was a cure for every illness or sickness that is caused by inflammation, would you want it? Without further ado, I bring you the world's only inflammatory supplement!

• Antioxidant Betalains

What they are 

Betalains are the pigments that give the Nopal cactus fruit its vibrant pink color. But that’s just the beginning. They’re also natural antioxidants—and they’re only found in a few of the world’s plants.

The Nopal fruit isn’t just included in this small group of special plants, it actually leads the group by containing one of the highest amounts of betalains in all of nature.

How they heal 

When you drink Nopalea, you take these betalains into your system, where they begin to restore your vitality on a cellular level. By helping the body reduce the toxins surrounding your cells and enabling essential nutrients to reach each cell, the betalains in Nopalea can reduce the inflammation in your body that leads to disease.

Scientific research shows that betalains help to:

• Reduces the risk of blood clots—betalains protect the thin lining of your blood vessels; this helps reduce the inflammation that makes your blood sticky and leads to clots.¹
• Reduces bad cholesterol—betalains strongly reduce oxidized LDL cholesterol.²
• Protects cells from toxins—betalains protect many types of cells, especially brain cells, from toxins known to trigger tumors.³
• Protects your liver—betalains provide significant protection from toxins that directly affect your liver.⁴

• Health Benefits

The power of betalains 

Harnessing the power of betalains, a rare and potent class of antioxidants that flourish in the Nopal cactus, Nopalea delivers scientifically proven health benefits.

Detoxify your body 

Every day, we’re exposed to toxins in our air, water and food—and even toxins created by our own bodies. Nopalea combines its betalains with other anti-toxic ingredients to combat these poisons where they strike us first: right inside the trillions of cells in our bodies.

By increasing the activity of CYP-2E1, a special enzyme that neutralizes daily toxins, Nopalea protects your cells and vital organs—especially your liver—against the carcinogens, hormone disruptors, respiratory toxins, developmental toxins and neurotoxins that are responsible for one-quarter of all the world’s diseases.

Reduce inflammation 

When toxins assault your system—or when injury or infection strikes—your body responds with a complex biological process commonly referred to as inflammation. If this inflammation goes unchecked, it can lead to a wide variety of disorders, from stroke to arthritis to heart disease.

Nopalea specifically targets signs of inflammation in your body and reduces them quickly.¹ Its betalains and other anti-inflammatory ingredients work directly on the fluid surrounding your cells. There, they draw off the toxins and excess water to reduce inflammation and rebalance the cellular environment.

Protect against premature aging 

Your skin is a miraculous covering that protects you from harm. Pollution, toxins, radiation and other potentially damaging influences are kept out of your body by your skin; vital organs are protected inside. One of the first signs of aging is thin, sagging, withered skin that is easily damaged.

Nopalea rushes to these damaged areas to shore up your protective layer. The betalains in Nopalea fill in the gaps of your cells (including the cells in your skin) and return them to the firm, robust nature of young cells — at any age. By providing a healthy environment for the cell, betalains keep it from withering.

More health benefits 

Want even more reasons to drink Nopalea? Scientific research shows that Nopalea also helps the body to:

• Increase energy
• Boost the immune system
• Protect against fluid retention
• Neutralize free radicals

Drink it and thrive.

• Sonoran Harvested

Low-impact harvesting 

Using sustainable wildcrafting techniques learned from native Sonoran ancestors, Nopalea takes only what’s needed from the extraordinary Nopal cactus. We leave most of the fruit on the plant to nourish the desert animals and ensure an abundant crop for future harvests. It’s our way of giving back, respecting the cycle of life and celebrating the harvest season.

High-impact wellness 

Immediately after harvesting, we transport the Nopal fruits to our state-of-the-art processing plant, where they’re juiced to a puree and blended with other all-natural ingredients to create a deliciously unique concentrated wellness drink. Using aseptic, sterile bottling techniques, we preserve the fruits’ purity and freshness—and we ensure the potency of its powerful antioxidant betalains.

• Research & Science

The Nopal cactus has been called a superfruit. That’s because its powerfulantioxidant betalains have been known to boost the health and well-being of all who drink in its powers.

But don’t just take our word for it. See what the scientific research community has to say.

Anti-Toxin activity

• “Cactus (Opuntia ficus-indica) protects against oxidative damage induced by the mycotoxin zearalenone in Balb/C mice.” (Food Chem Toxicol. 2008 May;46(5):1817-24.)
• “Opuntia ficus indica extract protects against chlorpyrifos-induced damage on mice liver.” (Food Chem Toxicol. 2008 Feb;46(2):797-802.)
• “Opuntia ficus indica (L.) Mill. fruit juice protects liver from carbon tetrachloride-induced injury.” (Phytother Res. 2005 Sep;19(9):796-800.)

Anti-Inflammatory

• “An anti-inflammatory principle from cactus.” (Fitoterapia. 2001 Mar;72(3):288-90)
• “Antioxidant betalains from cactus pear (Opuntia ficus-indica) inhibit endothelial ICAM-1 expression.” (Gentile C, Tesoriere L, Allegra M, Livrea MA, D’Alessio P. Ann N Y Acad Sci. 2004 Dec;1028:481-6.)
• “Effect of Opuntia ficus indica on symptoms of the alcohol hangover.” (Wiese J, McPherson S, Odden MC, Shlipak MG. Arch Intern Med. 2004 Jun 28;164(12):1334-40.)

Immune System Boost

• “Betalains a betacyanin pigment purified from fruits of Opuntia ficus-indica induces apoptosis in human chronic myeloid leukemia Cell line-K562.” (Phytomedicine. 2007 Nov;14(11):739-46.)
• “Antioxidant betalains from cactus pear (Opuntia ficus-indica) inhibit endothelial ICAM-1 expression.” (Ann N Y Acad Sci. 2004 Dec;1028:481-6.)
• “Modulation of intracellular calcium concentrations and T cell activation by prickly pear polyphenols.” (Mol Cell Biochem. 2004 May;260(1-2):103-10.)

Brain Protection

• “Inhibition of nitric oxide synthase expression in activated microglia and peroxynitrite scavenging activity by Opuntia ficus indica var. saboten.” (Phytother Res. 2006 Sep;20(9):742-7.)
• “Interventions for protecting against or treating alcohol hangover: systematic review of randomised controlled trials.” BMJ. 2005 Dec 24;331(7531):1515-8.)
• “Opuntia ficus-indica attenuates neuronal injury in in-vitro and in vivo models of cerebral ischemia.” (J Ethnopharmacol. 2006 Mar 8;104(1-2):257-62.)
• “Effect of Opuntia ficus indica on symptoms of the alcohol hangover.” (Arch Intern Med. 2004 Jun 28;164(12):1334-40.)
• “Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten.” (Brain Res. 2003 Mar 7;965(1-2):130-6.)

• Ingredients

SUPPLEMENTAL FACTS 

Serving Size 2 tbsp (1 fl oz) (30 mL) 
Servings per Container 32

Amount per Serving

%Daily Value*

Calories	11	0%
Calories from Fat	0	0%
Total Fat	<1>	0%
Cholesterol	0 g	0%
Sodium	.76 mg	0%
Total Carbohydrate	2.84 g	1%
Dietary Fiber	.32 g	0%
Sugars	2 g	0%
Protein	88 mg	0%
Vitamin C	2.5 mg	4%
Calcium	5.6 mg	0%
Iron	.1 mg	1%
Proprietary blend (Nopalea)	Total 907.15 g	†

Water (filtered), Opuntia concentrate (nopal concentrate), Agave Nectar, Grape Seed extract (vitis vinifera), Raspberry extract (rubus idaeus), Strawberry extract (fragaria chiloensis), Cranberry extract (vaccinium macrocarpon), Apple extract (malus omestica), Apricot extract (prunus armeniaca), Mango extract (mangifera indica) fruit, Orange concentrate (citrus aurantium) juice, Papaya concentrate (carica papaya fruit with papain), Tomato concentrate (lycopersicon esculentum) fruit, Kiwi concentrate (actinidia chinensis), Guava (psidium guajava powder), Lemon concentrate (citrus lionum juice), Opuntia concentrate (nopal concentrate) powder, Peach concentrate (prunus persica) juice, Pomegranate extract (punica granatum with ellagic acid and punocaligans), Green Tea extract (camellia sinensis), Beet (beta vulgaris) juice, Bilberry concentrate (vaccinium myrtillus), Acerola cherry extract (malphigia glabra), Amylase, Cellulase, Hemicellulase, Proteases [bromelain from pineapple (ananas comosus) and papain (carica papaya) from papaya, lipase, phytase], Stevia extract (stevia rebaudiana) leaf, Guar gum, Maltodextrin, Natural flavor, Cherry powder, Xanthum gum.

* Percent Daily Values are based on a 2,000 calorie diet. 

† Daily Value not establised.

• Secret Killer

To view this brochure on the reasons inflammation effects us all visit The Secret Killer.

If you would like to order Sonoran Bloom Nopalea or have further questions, you can do so by visiting SonoranBloom.com/13380527

Fibromyalgia: Helped With A Better Diet

     So, I recently had a teeny, tiny fender bender while running an errand for my dad's company. Is was quite an hike and partially inconvenient. What could have been an exchange of phone numbers and asta la vista turned into a fiasco. At one point, she claimed she developed fibromyalgia due to the terrible, terrible accident. Considering the zero amount of damage; it was quite the fib. My lack of compassion for her grew to curiosity, what is this disease and how can you get it? Is this reversible by a change in health habits and exercise? Long story short, her claim for fibromyalgia didn't fly, and here is why.

How It Works: Fibromyalgia

     Fibromyalgia is caused by a low level of serotonin in your blood. When serotonin is low, it increases pain sensitivity. Serotonin is a neurotransmitter that works to

 calm, soothe, and reduce anxiety. Now, the body has its own endorphin painkillers, but if serotonin is low then substance P amplifies pain signals.

Causes: Fibromyalgia

     This can be genetic in the sense you can be prone to it. It is common amongst those who lack physical activity and eat poorly. It also intensifies with one who is also struggling with depression. It is prevalent in women especially those who are experiencing menopause or just a loss of estrogen. Trauma to the central nervous system can also cause this disease.

What Doctor Mercola Says:

     Studies have not been proven that foods will fix chronic diseases such as Fibromyalgia. These health tips can apply to all peoples fighting obesity, high blood pressure, high cholesterol and/or diabetes.

Suggestions For Those With Chronic Illness:

• Limit Sugar as Much as Possible- Insulin (sugar) increases pain levels. Grains are metabolized as sugar so limit intake of grains as well.

• Eat Fresh Foods- Foods containing additives work against you increasing

 symptoms.

• Avoid Caffeine- Fibromyalgia's symptoms include fatigue, this means caffeine will prolong this symptom and increase tiredness in the long run.

• Try Avoiding Nightshade Vegetables- Tomatoes, Potatoes, and Eggplant

• Be Careful with Fats- Animal fats that contain omega-3 fats tend to aid in inflammation and pain.

• Use Yeast Sparingly- Yeast can contribute to yeast fungus which can contribute to pain.

• Avoid Pasteurized Dairy- This is easily digested by those struggling with this chronic illness. Especially organic grass-fed cow milk.

• Cut Down on Carbs- If you deal with chronic illness you have low adrenal functioning, lowering your carb intake can help avoid hyperglycemia.

• Avoid Aspartame- This artificial sweetener is found in sugar-free products and diet soda contains a chemical called excitotoxins. This activates neurons and increase pain sensitivity. Sugar-free foods are usually high in carbs (which convert to sugar) so try to avoid all together.

• Avoid Additives- Food additives increase pain sensitivity such as Monosodium Glutamate (MSG).

• Limit Junk Food- Junk food tears down your immune system, disrupts your sleep, and irritates your muscles. Junk food of course contributes to weight gain which increases the amount of pain.

You may not suffer from fibromyalgia, but you have to take care of yourself so you can avoid this horrible disease. Educating yourself is one of the best ways to be healthy! Stay healthy my friends!

Sources: Health.com, Mercola.com, WebMD.com, National Fibromyalgia Association